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Is NAD IV Therapy Safe?
Modwella- May 10
- 6 min read
NAD IV therapy is growing in popularity, and more people are including it in their health routines. As interest increases, so do the questions. One of the most common concerns is whether NAD IV therapy is safe. Like any wellness treatment, it’s important to understand how it works, what to expect, and how to approach it in a way that supports your goals while protecting your health.
NAD stands for nicotinamide adenine dinucleotide. It’s a coenzyme that exists naturally in your body and plays a role in many important processes. When used through an IV infusion, NAD can support energy levels, mental clarity, and overall cellular health. But just like with any supplement or treatment, it’s not one-size-fits-all. If you’re considering NAD as part of your wellness plan, this guide will help you understand what’s involved so you can make a choice that feels right for you.
Common and Potential Side Effects of NAD IV Therapy
Most people tolerate NAD IV therapy well, but like any supplement or treatment, it's important to understand how your body might respond. Side effects are not guaranteed, but knowing what to look for helps you stay informed and prepared.
Mild and Temporary Effects
Some people feel minor discomfort during or after a session. This can include things like:
Headache
Flushing or warmth in the face or chest
Nausea
Cramping or tightness in the stomach
Feeling pressure or heaviness in the chest
These effects usually happen if the NAD infusion is administered too quickly. A slower drip rate often helps reduce or prevent them. Your Modwella nurse will monitor you closely and adjust the speed if needed to make the experience more comfortable.
Reactions at the Injection Site
It’s also possible to feel soreness where the IV was placed. This might include redness, slight swelling, or sensitivity in the arm. These are common with any IV treatment and typically go away within a day.
Adjusting to the Treatment
As NAD+ works through your body, you might feel tired or foggy for a short time afterward. This happens because your cells are adjusting and using the new coenzyme. For most people, this feeling fades quickly and is followed by more energy, clearer thinking, or an overall boost in well-being.
When to Talk to a Healthcare Provider
While NAD IV therapy is considered safe for most people, it’s still important to make sure it’s the right fit for your body. Modwella takes this seriously. Before your first NAD IV treatment, you’ll meet with one of Modwella’s licensed nurse practitioners for a brief telehealth appointment. During this visit, they’ll review your medical history, current health conditions, and any medications or supplements you’re taking.
This step helps ensure the treatment is both safe and effective for your needs. The nurse practitioner will let you know if any adjustments are needed or if another option might be a better fit. This makes Modwella’s process not only convenient but also focused on safety and personalized care.
What Affects How Your Body Responds to NAD IV Therapy?
Not everyone feels the same way after NAD IV therapy. That’s because your body’s response depends on several factors. Understanding these can help you set clear expectations and get the most from your treatment.
Your Current NAD+ Levels
If your NAD+ levels are already low, which can happen due to age, stress, or certain health issues, you may notice a more noticeable difference after treatment. People who are more depleted often feel results sooner because their bodies are getting something they need.
Health History and Medical Conditions
Your overall health can change how your body responds to NAD+. If you’ve been diagnosed with conditions like chronic fatigue syndrome, autoimmune issues, or neurodegenerative diseases such as Parkinson's or Alzheimer's, your experience might differ. This doesn’t mean NAD+ therapy won’t help, but your response may look different compared to someone without these concerns.
Medications and Supplements
Some medications and supplements may affect how your body uses NAD+. Drugs that influence blood pressure, metabolism, or hydration can shift how you feel during or after treatment. This is why it’s important to tell your Modwella provider about anything you’re currently taking so they can be prepared to help you.
Lifestyle Factors
Your sleep, nutrition, hydration, and stress levels all play a role in how your body responds. NAD+ supports energy metabolism, but that process works better when your body already has the support it needs. Getting enough water, eating well, and resting when you can may help improve your overall results.
Previous Exposure to NAD or Related Therapies
If you’ve taken oral NAD supplements before, or used vitamin B3, NADH, or other precursors, your body may already be prepared to use NAD+ efficiently. If you’re new to NAD+ therapy, it might take a few sessions before the benefits start to build.
Who Should Avoid NAD IV Therapy or Use It with Caution
NAD IV therapy can be a helpful option for many people, but there are certain cases where extra care is needed. If you have any health concerns, it’s important to speak with a healthcare provider before starting treatment. Modwella’s nurse practitioner team will guide you through this during your intake appointment to make sure the therapy is safe for you.
Pregnancy and Breastfeeding
There hasn’t been enough research yet to confirm whether NAD IV therapy is safe during pregnancy or while breastfeeding. Until more is known, it’s best to avoid NAD treatments during this time unless your healthcare provider recommends otherwise.
Low Blood Pressure
NAD IV therapy may cause a temporary drop in blood pressure for some people, especially if the drip is too fast. If you already have low blood pressure or are on medications that affect it, be sure to let your provider know in advance so they can adjust your treatment as needed.
Certain Chronic Conditions
If you have a history of kidney disease, liver issues, or other serious medical conditions, NAD+ therapy might not be the right choice without medical supervision. People with these concerns may need special monitoring or a different approach to treatment.
Active Illness or Dehydration
If you're currently sick or feeling dehydrated, it’s important to wait until you’ve recovered before scheduling a session. While hydration is part of NAD IV therapy, starting treatment while unwell may affect how your body responds or increase the chances of side effects.
History of Adverse Reactions to IV Treatments
If you’ve had reactions to IV infusions in the past, including cramping, nausea, or dizziness, let your provider know beforehand. This will help them adjust the drip rate and ingredients to reduce the risk of discomfort during your session.
What the Research and FDA Say About NAD IV Therapy
NAD IV therapy is becoming more popular, but it’s still a newer option in the world of wellness. Because of this, many people wonder how it’s viewed by researchers and medical organizations. Understanding what’s known so far can help you make informed decisions about trying it.
What Clinical Research Shows
Early studies on NAD+ have shown promise. Research has looked at how NAD+ supports cellular energy, DNA repair, and brain health. Some clinical trials are exploring its role in managing age-related decline, addiction recovery, and certain neurodegenerative conditions. These include conditions like Parkinson’s and Alzheimer’s, where NAD+ may play a part in supporting brain cells and slowing down damage from oxidative stress.
Although research is ongoing, the results so far are encouraging. Many experts believe that supporting NAD+ levels could help with long-term health, but larger and more detailed studies are still needed to fully confirm the benefits and safety over time.
FDA Status and Oversight
Right now, NAD+ is not approved by the U.S. Food and Drug Administration (FDA) as a treatment for any specific disease. That doesn’t mean it’s unsafe. It means it’s considered a supplement or wellness tool, not a drug for curing or preventing medical conditions.
The ingredients used in NAD IV therapy, including sterile saline and the NAD+ compound itself, must meet safety and quality standards. At Modwella, all treatments are prepared by licensed medical professionals using high-quality supplies to protect your health and meet regulatory expectations.
Why Ongoing Research Matters
The science around NAD+ is still growing. As more studies are done, we’ll better understand how NAD supplementation works, what the long-term effects are, and which people benefit the most. Until then, it’s important to work with trained providers and be aware of both the potential benefits and the limits of current research.
Book NAD IV Therapy with Modwella Today
Modwella offers NAD IV therapy and other wellness treatments to help you feel your best with support you can trust. If you're considering NAD for energy, mental clarity, or overall health, our team is here to make the process simple and safe. Every client completes a quick telehealth visit with a licensed nurse practitioner to ensure NAD IV therapy is right for them.
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